AI & Agent Evaluation
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Introducing GeneBench-Pro

benchmark release · source date 2026-06-30 · added 2026-08-07 15:52:43 · updated 2026-08-07 15:52:43 · Open original blog

Problems / challenges / motivations

  • Scientific-reasoning benchmarks mostly test recall or single-step analysis, not the judgment calls that make research hard.
  • Real analysis has dependent decision forks: an early wrong turn invalidates everything downstream.
  • Benchmarks authored by a lab whose models top them are easy to discount.

Key ideas

  • 129 research-level problems measuring "research taste" — multi-stage, judgment-heavy computational-biology analysis with dependent decision forks.
  • Grading is deterministic, run on synthetic data with known causal structure, so the right answer is defined by construction rather than by a judge.
  • GPT-5.6 Sol reaches 28.7% (31.5% Pro); the strongest non-GPT baseline is Claude Opus 4.8 at 16.0%.
  • The companion paper documents estimand-based grading, external review of 82 problems, and a 50-problem holdout handed to Artificial Analysis for third-party benchmarking.

Why it matters for evals

  • The holdout hygiene is the interesting part: giving a third party a private slice is a cheap, copyable defense against both contamination and self-scoring.
  • The results highlight a "noticing versus acting" gap — models often identify the right concern but fail to act on it across a long analysis.
  • Caveat: OpenAI-authored and its models top the leaderboard; the third-party holdout partly but not fully mitigates that.

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